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So it’s the holiday weekend and many of you all will engage in dangerous behavior this weekend but before you do I have a special warning for you! It’s very common for people to mix alcohol and pain killers even though they know better. Why would people do this? Well because alcohol can enhance the effects of these drugs. So if you are feeling “high” – then you will feel “higher”.

The FDA recently notified healthcare professionals of changes to the Warnings section of the prescribing information of tramadol/acetaminophen combination (Ultracet) and tramadol (Ultram).  So I figured I would share some knowledge with you all and remind you of some things to be cognizant of.

Tramadol is a centrally acting synthetic opioid analgesic indicated for the management of moderate to moderately severe chronic pain. The strengthened warning emphasizes the risk of suicide for patients who are addiction prone, taking tranquilizers or antidepressants (Zoloft, Prozac…etc).  Tramadol-related deaths have occurred in patients with previous histories of emotional disturbances or suicidal ideation or attempts, as well as history of misuse of other drugs. Tramadol may have additive effects when used in conjunction with alcohol, other opioids or illicit drugs that cause central nervous system depressions.  Tramadol has abuse potential and patients need to be aware since you can find it in many medicine cabinets!

Watch this quick video for more information and leave a comment below.


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Filed under: FDA Updates

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